top of page
Latest News
Australian research identifies significant opportunity to reduce major cardiac and respiratory events in people with COPD, a leading cause of preventable hospitalisations
This real-world study of Australian primary care data shows that high-risk* COPD, characterised by recent breathing flare-ups, is...
1 day ago3 min read
Breathing Easier: Our Quest to Transform COPD Management in Primary Care
Our latest article in Primary Health Care Research and Development details the route to successful implementation of a novel programme ...
2 days ago2 min read
Minimizing Steroid Burden in Severe Asthma: Real-World Data Demonstrate Biologics as a Game Changer
Drawing on data from over 5,600 severe asthma patients across real-world specialist and primary care settings in 22 countries, the SOLAR...
Jun 33 min read
PREVAIL Trial Protocol: Early Intervention in Modifiable High-Risk COPD
Our latest manuscript in the Journal of the COPD Foundation describes the protocol for PREVAIL , the first clinical trial to test...
Jun 32 min read
Biologics for asthma prevent new-onset diabetes, major adverse cardiovascular events (MACE) as well as other oral corticosteroid (OCS)-related adverse events: Ground-breaking results from SOLAR II
The real-world SOLAR II study shows that biologic initiators had 18% lower risk of developing any oral corticosteroid (OCS)-related...
May 193 min read
A recent study shows a surprising improvement in respiratory outcomes when patients with asthma receive weight loss drugs.
Singapore, [10 April 2025] – A large real world evidence study conducted by leading respiratory experts found patients with asthma who...
Apr 82 min read
Innovative analysis predicts steroid-related health risks for people with asthma
Singapore, [8 April 2025] – Groundbreaking research by the Observational and Pragmatic Research Institute (OPRI) has developed...
Apr 82 min read
Switching or stopping biologic therapy was associated with worse clinical outcomes than continuing the initial therapy: Results from CLEAR
A recently published study in Pragmatic and Observational Research, “Real-world biologic use patterns in severe asthma, 2015–2021: the...
Mar 183 min read
Global disease burden of patients with severe asthma, regardless of biologic accessibility and receipt of biologic treatment: Results from EVEREST
The EVEREST study published in the Journal of Asthma and Allergy, “Disease Burden and Access to Biologic Therapy in Patients with Severe...
Oct 24, 20243 min read
Exploring different composite definitions of responders to biologic treatment for severe asthma (FULL BEAM Response)
The International Severe Asthma Registry (ISAR) ’s new study, “ Exploring definitions and predictors of response to biologics for severe...
Jul 10, 20243 min read
Exploring definitions and predictors of severe asthma clinical remission post-biologic in adults (FULL BEAM Remission)
We are excited to share groundbreaking findings on remission as a therapeutic target in " Exploring definitions and predictors of severe...
Jul 9, 20242 min read
International research collaboration affirms benefits of biologic therapies across broad severe asthma patient populations worldwide, but also highlights unmet treatment needs: Results from LUMINANT
Singapore, [25 June 2024] – A new analysis of data from the International Severe Asthma Registry (ISAR) has revealed a spectrum of...
Jun 25, 20243 min read
Ground-breaking new study from ISAR uncovers the power of asthma tests BEC and FeNO to predict effectiveness of biologic therapies in Severe Asthma
A new real-world research study from ISAR, the International Severe Asthma Registry, reveals the strength of the asthma tests...
May 8, 20242 min read
New ISAR Research Sheds Light on Asthma Exacerbation Rates: Great Variability Found Across Nations
The International Severe Asthma Registry is a global collaborative initiative to gather anonymous, longitudinal, real-life data for...
Apr 25, 20241 min read
Thirty-year trends analysis reveals continuous overuse of systemic glucocorticoids to treat patients with asthma in the United Kingdom
Singapore, [19 April 2024] – Analysis of data from the Optimum Patient Care Research Database (OPCRD) has shown high rates of systemic...
Apr 19, 20242 min read
New evidence reveals the power of biologics to improve severe asthma outcomes in patients with T2 comorbidities
ISAR’s new publication "Association between T2-related co-morbidities and effectiveness of biologics in severe asthma” to the highly...
Mar 14, 20241 min read
Latest ISAR research reveals the significant impact of pre-existing health on response to treatment with biologics in Severe Asthma
Important progress has been gained in the journey towards understanding response to biologic therapy in severe asthma through the...
Feb 22, 20242 min read
Pioneering Study Reveals No Increased Pneumonia Risk in COPD Patients Using Extrafine Beclometasone Dipropionate in Inhaler Therapy
A ground-breaking study conducted by an international consortium of leading respiratory experts sheds new light on the management of COPD
Feb 21, 20242 min read
Observational and Pragmatic Research International Joins the Good Business Charter
Observational and Pragmatic Research International Limited is delighted to announce that it has signed up to the Good Business Charter (GBC)
Feb 2, 20243 min read
LANDMARK STUDY REVEALS ADVERSE OUTCOMES LINKED TO ORAL CORTICOSTEROID USE IN COPD PATIENTS
Singapore, [4 December 2023] - Results from a real-world research study have highlighted the risks associated with the long-term use of...
Dec 12, 20232 min read
bottom of page